abstract：:The E/A ratio (of peak mitral blood flow velocity during early diastole to that during atrial contraction) has limitations in the assessment of diastolic function. Previous studies have suggested that peak blood flow velocity is normally maintained or increased towards the cardiac apex but that it decreases in diastol...

journal_title：Journal of human hypertension

authors： Chapman JN,Mayet J,Foale RA,Thom SA

更新日期：1999-12-01 00:00:00

abstract：:Determining blood pressure (BP) values at different daily time periods is a well recognised measure to assess the risk of end-organ damage. However, the use of various definitions of these periods, eg, day vs night, sleep vs wake or arbitrary definitions, makes clinical decisions based on available data difficult. In ...

journal_title：Journal of human hypertension

authors： Eissa MA,Yetman RJ,Poffenbarger T,Portman RJ

更新日期：1999-11-01 00:00:00

abstract：:To elucidate whether auscultation of the Korotkoff sounds inside the cuff and in the antecubital fossa leads to different blood pressure (BP) values we measured BP at both sites simultaneously with identical flat stethoscopes in a same-arm test design (part A) in 64 normotensive (N: 32 men, 32 women; mean age: 38.7 +/...

journal_title：Journal of human hypertension

authors： Weber F,Anlauf M,Hirche H,Roggenbuck U,Philipp T

更新日期：1999-10-01 00:00:00

abstract：:The purpose of this study is to review the role of dopamine in hypertension and associated conditions. The analysis of literature indicates that present knowledge is mostly based on poor markers and indirect evidence of dopaminergic activity and only few molecular biological data. Alternative markers such as plasma do...

journal_title：Journal of human hypertension

authors： Kuchel O

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVES:It has been suggested that hypertensives at high risk of cardiovascular complications can be identified on the basis of their left ventricular mass as determined echographically. However, there is as yet a lack of consensus on the mode of indexation (body surface area, height, height 2.7) of left ventricular...

journal_title：Journal of human hypertension

authors： Gosse P,Jullien V,Jarnier P,Lemetayer P,Clementy J

更新日期：1999-08-01 00:00:00

abstract：:Studies of populations or communities with no rise in blood pressure (BP) with advancing age and low prevalence of hypertension, may provide aetiological clues on the cause of hypertension. Within westernised societies, low blood pressures have been reported amongst chronic psychiatric in-patients and closed order sec...

journal_title：Journal of human hypertension

authors： Lip GY,Douglas M,Gupta A,Beevers DG

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Hypertension is an important public health problem, with some variability of its epidemiological properties in different populations. OBJECTIVES:The purpose of this study was to estimate the prevalence of hypertension and to determine the hypertension awareness, treatment and control rates in Aydin, a Turki...

journal_title：Journal of human hypertension

authors： Sönmez HM,Başak O,Camci C,Baltaci R,Karazeybek HS,Yazgan F,Ertin I,Celik SC

更新日期：1999-06-01 00:00:00

abstract：:The kinetic properties of sodium-proton exchange are abnormal in human red blood cells of hypertensive patients and it has been demonstrated that the transport protein undergoes post-translational modifications able to affect its kinetic properties. Protein kinase C (PKC) activation decreases the affinity constant for...

journal_title：Journal of human hypertension

authors： Ceolotto G,Sartori M,Felice M,Clari G,Bordin L,Semplicini A

更新日期：1999-05-01 00:00:00

abstract：:This work examines the association between hypertension and hypothyroidism in geriatric patients seen at a primary care medical office. One hundred and twenty-two geriatric patients with elevated thyroid stimulating hormone (TSH) levels were selected for the study. An equal number of euthyroid geriatric individuals we...

journal_title：Journal of human hypertension

authors： Bergus GR,Mold JW,Barton ED,Randall CS

更新日期：1999-04-01 00:00:00

abstract：:The aim of the study was to investigate the impact of various blood pressure (BP) measurement methods on the assessment of differences in BP levels between patients with normoalbuminuric type 1 diabetes and healthy controls. We measured intra-arterial BP (i.a.), sphygmomanometric BP (sphygmo), 24-h ambulatory blood pr...

journal_title：Journal of human hypertension

authors： Vervoort G,Wetzels JF,Lutterman JA,Berden JH,Thien T,Smits P

更新日期：1999-02-01 00:00:00

abstract：:Hypertension is common in West Africa and likely to become more common as urbanisation increases. There are at present few facilities for the detection and management of hypertension so the influence it has on overall morbidity and mortality in the population is not clear. The objectives of the study were to assess: (...

journal_title：Journal of human hypertension

authors： Plange-Rhule J,Phillips R,Acheampong JW,Saggar-Malik AK,Cappuccio FP,Eastwood JB

更新日期：1999-01-01 00:00:00

abstract：:In an in vivo study, spontaneously hypertensive rats (SHR) were treated with an angiotensin II (Ang II) type 1 receptor antagonist of candesartan or hydralazine. Untreated SHR progressively developed severe hypertension, and treatment with candesartan or hydralazine decreased blood pressure. Candesartan reduced left v...

journal_title：Journal of human hypertension

authors： Yamazaki T,Yazaki Y

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:This study compares the antihypertensive efficacy and tolerability of valsartan, a novel angiotensin II antagonist, given with hydrochlorothiazide (HCTZ) vs placebo or vs valsartan or HCTZ alone. DESIGN:871 adult out-patients with essential hypertension participated in this double-blind study. Patients were ...

journal_title：Journal of human hypertension

authors： Benz JR,Black HR,Graff A,Reed A,Fitzsimmons S,Shi Y

更新日期：1998-12-01 00:00:00

abstract：:Beta-blockers are not very effective at lowering blood pressure in elderly hypertensive patients or in Afro-Caribbeans and these two groups represent a large proportion of people with raised blood pressure. Furthermore they do not prevent more heart attacks than the thiazide diuretics. Beta-blockers can also be danger...

journal_title：Journal of human hypertension

authors： Beevers DG

更新日期：1998-12-01 00:00:00

abstract：:To investigate blood pressure (BP) as well as other risk factors before the onset of myocardial infarction in hypertensive patients, we analysed the BP and metabolic variables in 94 hypertensive patients who had been followed up in our out-patient clinic before the first onset (M1 group; n = 42, 69 +/- 1 years, mean +...

journal_title：Journal of human hypertension

authors： Minami J,Kawano Y,Nonogi H,Ishimitsu T,Matsuoka H,Takishita S

更新日期：1998-10-01 00:00:00

abstract：:The treatment of hypertension in the elderly has to take into account co-existing pathology. However, the benefit from treatment are large in terms owing to the frequency of cardiovascular events in the elderly. The benefits observed in randomised controlled trials are reviewed together with the adverse effects of the...

journal_title：Journal of human hypertension

authors： Bonapace S,Rajkumar C,Bulpitt CJ

更新日期：1998-09-01 00:00:00

abstract：:The Dead Sea (barometric pressure: 800 mm Hg) is an important balneotherapeutic centre for chronic dermatologic and arthritic diseases. In the past, hypertensive patients have complained sporadically of weakness and dizziness during a stay in the Dead Sea. It was therefore recommended that hypertensives do not stay at...

journal_title：Journal of human hypertension

authors： Paran E,Neuman L,Sukenik S

更新日期：1998-08-01 00:00:00

abstract：:Published reports of 30 separate sets of analyses from 29 observational studies relating dietary intake of magnesium to blood pressure (BP) were identified through a comprehensive search using MEDLINE and BIDS-EMBASE. Three studies were prospective, 24 cross-sectional (25 reports), of which four also contained a longi...

journal_title：Journal of human hypertension

authors： Mizushima S,Cappuccio FP,Nichols R,Elliott P

更新日期：1998-07-01 00:00:00

abstract：:We compared the effects on blood pressure (BP) of three isocaloric diets with reduced total fat and saturated fatty acid (SAFA) contents but with different proportions of monounsaturated (MUFA) and polyunsaturated fatty acids (PUFA). Diet LF (low fat) provided 20 en% fat (7.9% SAFA, 7.8% MUFA, 3.0% PUFA); diet HP (hig...

journal_title：Journal of human hypertension

authors： Aro A,Pietinen P,Valsta LM,Salminen I,Turpeinen AM,Virtanen M,Dougherty RM,Iacono JM

更新日期：1998-06-01 00:00:00

abstract：:The renin-angiotensin system is central to the pathophysiology of a number of cardiovascular disorders. Most obviously this is so with renin secreting tumours, but the system is of central importance in other disorders such as scleroderma renal crisis and most cases of malignant hypertension. Activation of the renin-a...

journal_title：Journal of human hypertension

authors： Nicholls MG,Richards AM,Agarwal M

更新日期：1998-05-01 00:00:00

abstract：:The use of heart rate in clinical practice is limited by its variability under measurement situations. The mean heart rate on ambulatory monitoring provides a more robust statistic for clinical use. We examined the relationship between mean heart rate on initial referral ambulatory blood pressure monitoring (ABPM) to ...

journal_title：Journal of human hypertension

authors： Owens PE,Lyons S,O'Brien E

更新日期：1998-04-01 00:00:00

abstract：:It has been shown in animal experiments that angiotensin II and aldosterone have mitogenic effects on the cardiovascular system, whereas atrial natriuretic peptide has antimitogenic properties. The aim of the present study was to relate plasma renin activity, angiotensin II, aldosterone and atrial natriuretic peptide ...

journal_title：Journal of human hypertension

authors： Fagard RH,Lijnen PJ,Petrov VV

更新日期：1998-03-01 00:00:00

abstract：:Lipoprotein(a) (Lp(a)) is considered an important risk factor for coronary disease, cerebrovascular pathology and re-stenosis of coronary bypass. Few studies have been conducted on this lipoprotein in essential arterial hypertensive patients. The purpose of our study was to measure the serum concentrations of Lp(a) an...

journal_title：Journal of human hypertension

authors： Catalano M,Perilli E,Carzaniga G,Colombo F,Carotta M,Andreoni S

更新日期：1998-02-01 00:00:00

abstract：:Sodium-lithium countertransport activity has been proposed as a marker for hypertension and is lower in black compared to Caucasian subjects both with and without vascular disease. The question arises of what is the primary kinetic locus of the altered behaviour of the countertransporter in black subjects and whether ...

journal_title：Journal of human hypertension

authors： Hardman TC,Croft P,Morrish Z,Anto-Awoakye K,Lant AF

更新日期：1998-01-01 00:00:00

abstract：:This study investigated the period of time that blood pressure (BP) should be measured at home in older patients in order to obtain steady BP values. Thirty-six men and 38 women (> or =60 years) were recruited at one family practice. At one office visit the family physician measured supine, sitting and standing BPs th...

journal_title：Journal of human hypertension

authors： Celis H,De Cort P,Fagard R,Thijs L,Staessen JA

更新日期：1997-10-01 00:00:00

abstract：:Stroke is a very common cause of death and disability. Several lines of evidence point to stroke as a polygenic multifactoral phenotype and there are also a number of well studied single gene Mendelian stroke conditions. Rat models have identified several chromosomal sites linked to stroke, and this together with othe...

journal_title：Journal of human hypertension

authors： Carter ND

更新日期：1997-09-01 00:00:00

abstract：:It has been suggested that the deletion polymorphism of the angiotensin-converting enzyme (ACE) genotype may be important in the development of left ventricular hypertrophy (LVH). In order to test this hypothesis we investigated the interaction between blood pressure (BP), LVH and ACE genotype in 86 previously untreat...

journal_title：Journal of human hypertension

authors： Mayet J,O'Kane KP,Elton R,Johnstone HA,Shahi M,Ozkor MA,Stanton AV,Poulter NR,Sever PS,Foale RA,Webb DJ,Thom SA

更新日期：1997-09-01 00:00:00

abstract：:Candesartan cilexetil is rapidly and completely hydrolysed to the active compound candesartan during absorption from the gastrointestinal tract. Candesartan is a potent, long-acting, selective angiotensin II AT1 receptor blocker. The pharmacokinetics of candesartan were investigated after single and repeated once-dail...

journal_title：Journal of human hypertension

authors： Hübner R,Högemann AM,Sunzel M,Riddell JG

更新日期：1997-09-01 00:00:00

abstract：:Hypertension is a common and potentially serious disease and accurate measurement of blood pressure (BP) is important for its diagnosis and management. The aim of this study was to assess the knowledge of hospital staff on the basic principles of BP measurement. Consultants, junior doctors and nurses in a large teachi...

journal_title：Journal of human hypertension

authors： Ahmed ME

更新日期：1997-08-01 00:00:00

abstract：:Altitude affects blood pressure (BP) depending on duration and absolute altitude of exposure. Until now changes in BP during exposure to altitude were studied only in Caucasians. It is not known whether BP is affected differently in black and white people in response to altitude. During a 6-day climb on Kilimanjaro, B...

journal_title：Journal of human hypertension

authors： Hasler E,Suter PM,Vetter W

更新日期：1997-07-01 00:00:00

abstract：:In view of the concern regarding the potential risks and benefits of sodium restriction, the effect on biochemical and orthostatic responses from a moderate reduction in sodium intake in elderly persons that is sufficient to lower systolic blood pressure (SBP) was examined. Seventeen hypertensive subjects aged 65-79 y...

journal_title：Journal of human hypertension

authors： Fotherby MD,Potter JF

更新日期：1997-06-01 00:00:00

abstract：:The present study was designed to compare the effects of angiotensin-converting enzyme (ACE) inhibitors and calcium antagonists-the two drug classes thought to be most effective in reducing left ventricular hypertrophy-on arterial pressure, left ventricular structure and function in patients with essential hypertensio...

journal_title：Journal of human hypertension

authors： Aepfelbacher FC,Messerli FH,Nunez E,Frohlich ED

更新日期：1997-05-01 00:00:00

abstract：:The purpose of the study was to evalute the impact of the renin-angiotensin-aldosterone (RAA) system on blood pressure (BP) response in patients with hypertensive emergencies and urgencies treated with intravenous enalaprilat. Thirty-five patients with a systolic BP (SBP) >210 mm Hg and/or diastolic BP (DBP) >110 mm H...

journal_title：Journal of human hypertension

authors： Hirschl MM,Binder M,Bur A,Herkner H,Woisetschläger C,Bieglmayer C,Laggner AN

更新日期：1997-03-01 00:00:00

abstract：:Blood pressure (BP) during siesta declines to levels similar to those of night time sleep. The objective of the study was to assess the effect of siesta on 24-h ambulatory BP (ABP) data. Two different approaches were employed for the definition of day and night periods: (1) actual patient reported day and night interv...

journal_title：Journal of human hypertension

authors： Stergiou GS,Malakos JS,Zourbaki AS,Achimastos AD,Mountokalakis TD

更新日期：1997-02-01 00:00:00

abstract：:Since endothelin production is stimulated in vitro by insulin, we performed this study to evaluate in vivo the relationships between endothelin and insulin plasma levels during a glucose load. We studied 28 subjects; 17 with normal glucose tolerance (NGT) and 11 with impaired glucose tolerance (IGT). Ten of the subjec...

journal_title：Journal of human hypertension

authors： Andronico G,Mangano M,Ferrara L,Lamanna D,Mulé G,Cerasola G

更新日期：1997-01-01 00:00:00

abstract：:The genetic mechanisms responsible for the formation of adrenocortical adenomas which autonomously produce aldosterone are largely unknown. The adrenal renin-angiotensin system has been implicated in the pathophysiology of these tumours. Angiotensin-converting enzyme (ACE) catalyses the generation of angiotensin II, a...

journal_title：Journal of human hypertension

authors： Tunny TJ,Xu L,Richardson KA,Stowasser M,Gartside M,Gordon RD

更新日期：1996-12-01 00:00:00

abstract：:The prevalence of microalbuminuria in patients with essential hypertension ranges between 10 and 25%. The level of albuminuria is highly correlated with arterial pressure and more closely ambulatory arterial pressure. The interaction between albuminuria and arterial pressure is clearly enhanced by overweight and smoki...

journal_title：Journal of human hypertension

authors： Mimran A,Ribstein J

更新日期：1996-10-01 00:00:00

abstract：:In order to find out the general public's opinion on blood pressure (BP) control in Poland a poll was conducted on a representative sample of 2080 randomly selected subjects. Overall 71% of the subjects were aware of their BP level. The awareness of BP level increased progressively with age and education level. Among ...

journal_title：Journal of human hypertension

authors： Krupa-Wojciechowska B,Narkiewicz K,Rynkiewicz A

更新日期：1996-09-01 00:00:00

abstract：:An association of obesity and hypertension is well recognised and there is a direct positive relationship between body weight or body mass index (BMI) and blood pressure (BP), although the mechanisms responsible for weight-related increases of BP are still unknown. Obesity does appear to be an independent risk factor ...

journal_title：Journal of human hypertension

authors： Efstratopoulos AD,Voyaki SM,Lydakis H,Meikopoulos M,Hini S,Tsikinis Y

更新日期：1996-09-01 00:00:00

abstract：:The value of microalbuminuria in predicting hypertensive complications in pregnant patients at high risk was tested in a prospective trial. A total of 276 patients were studied (142 in the study group vs 134 controls). Albumin was measured in 8-h overnight urine collection throughout pregnancy using radioimmunoassay t...

journal_title：Journal of human hypertension

authors： Bar J,Friedman S,Erman A,Kaplan B,Hod M,Boner G,Ovadia J

更新日期：1996-09-01 00:00:00